publication . Article . 2008

Chemokines and Cardiovascular Risk

Pål Aukrust; Bente Halvorsen; Arne Yndestad; Thor Ueland; Erik Øie; Kari Otterdal; Lars Gullestad; Jan K. Damås;
Open Access
  • Published: 01 Aug 2008 Journal: Arteriosclerosis, Thrombosis, and Vascular Biology, volume 28, pages 1,909-1,919 (issn: 1079-5642, eissn: 1524-4636, Copyright policy)
  • Publisher: Ovid Technologies (Wolters Kluwer Health)
Abstract
Based on the importance of inflammation in atherogenesis, recent work has focused on whether plasma markers of inflammation can noninvasively diagnose and prognosticate atherosclerotic disorders. Although several studies support an important pathogenic role of chemokines in atherosclerosis, potentially representing attractive therapeutic targets in atherosclerotic disorders, this does not necessarily mean that chemokines are suitable parameters for risk prediction. In fact, the ability to reflect upstream inflammatory activity, stable levels in individuals, and high stability of the actual protein (eg, long half-life and negligible circadian variation) are addit...
Subjects
free text keywords: Cardiology and Cardiovascular Medicine
Powered by OpenAIRE Research Graph
Any information missing or wrong?Report an Issue