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Journal of Inorganic Biochemistry; ZENODO
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synthesis characterization and crystal structures of two pentagonal bipyramidal fe iii complexes with dihydrazone of 2 6 diacetylpyridine and girard s t reagent anticancer properties of various metal complexes of the same ligand

Authors: Katarina Anđelković; Milica R. Milenković; Andrej Pevec; Iztok Turel; Ivana Z. Matić; Miroslava Vujčić; Dušan Sladić; +4 Authors

synthesis characterization and crystal structures of two pentagonal bipyramidal fe iii complexes with dihydrazone of 2 6 diacetylpyridine and girard s t reagent anticancer properties of various metal complexes of the same ligand

Abstract

In this work synthesis, characterization and crystal structures of two isothiocyanato Fe(III) complexes with 2,2'-[2,6-pyridinediylbis(ethylidyne-1-hydrazinyl-2-ylidene)]bis[N,N,N-trimethyl-2-oxoethanaminium] dichloride (HPentagonal-bipyramidal Fe(III) complexes with dihydrazone of 2,6-diacetylpyridine and Girard's T reagent have been synthesized and characterized. Cytotoxic activity of Fe(III) complexes and Co(II), Ni(II), Mn(II), Zn(II) and Cd(II) complexes with the same ligand was tested. The best activity was observed in the case of Fe(III), Co(II) and Cd(II) complexes.

Country
Serbia
Keywords

Cell Death, Pyridines, Crystal structure, Cytotoxicity, Cell Cycle, Hydrazones, Antineoplastic Agents, Ferric Compounds, Betaine, Pentagonal-bipyramidal, Fe(III) complexes, A549 Cells, 2,6-diacetylpyridine dihydrazone, Humans, DNA interactions, K562 Cells, DNA Damage, HeLa Cells

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