publication . Article . 2011

Cell biology and immunology of Listeria monocytogenes infections: novel insights

Fabrizia Stavru; Cristel Archambaud; Pascale Cossart;
Restricted English
  • Published: 23 Feb 2011
  • Publisher: HAL CCSD
Listeria monocytogenes is an intracellular bacterium responsible for a disease characterized by several clinical features, such as septicemia, brain infection, abortion, and perinatal infection. These clinical features are attributed to its amazing capacity to cross several barriers in susceptible hosts. Intracellular infection is a consequence of the bacterium's capacity to enter a wide variety of mammalian cells, to not only survive but also replicate therein, and to its faculty to spread from one cell to the next, thereby escaping the humoral immune response. Here, we review both the well-established and the newly discovered strategies used by this bacterium ...
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free text keywords: bacterial infection, Toll-like receptors, phagocytosis, cytokines, ACTIN-BASED MOTILITY, NF-KAPPA-B, ACTIVATED PROTEIN-KINASE, MICROVASCULAR ENDOTHELIAL-CELLS, RECEPTOR TYROSINE KINASE, CYTOKINE GENE-EXPRESSION, inflammation, TUMOR-NECROSIS-FACTOR, CD8(+) T-CELLS, INNATE IMMUNE-RESPONSES, INTRACELLULAR BACTERIAL-INFECTION, [SDV]Life Sciences [q-bio], Immunology, Immunology and Allergy, Innate immune system, Listeria monocytogenes, medicine.disease_cause, medicine, Listeria, biology.organism_classification, biology, Phagocytosis, Inflammation, medicine.symptom, Toll-like receptor, Intracellular, Virology, Immunology, Immune system, Microbiology
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