publication . Article . 2014

Arbidol as a broad-spectrum antiviral: An update

Julie Blaising; Stephen J. Polyak; Eve Isabelle Pécheur;
Open Access
  • Published: 24 Apr 2014 Journal: Antiviral Research, volume 107, pages 84-94 (issn: 0166-3542, Copyright policy)
  • Publisher: Elsevier BV
Highlights • Arbidol (ARB) is licensed in Russia and China for the treatment of influenza and other viral infections. • ARB inhibits a large panel of viral pathogens, enveloped or not. • ARB displays a dual binding activity to lipid membranes and to viral or cellular proteins. • It blocks viral endocytosis and replication in membranous intracellular compartments.
Medical Subject Headings: urologic and male genital diseasesvirusesfemale genital diseases and pregnancy complicationscardiovascular diseaseshormones, hormone substitutes, and hormone antagonists
free text keywords: Virology, Pharmacology, Article, Arbidol, Influenza, Hepatitis C virus, Entry, Fusion, Antiviral therapy, Cellular functions, Encephalitis, medicine.disease, medicine, Hemorrhagic Fevers, Virology, Broad spectrum, business.industry, business, Immunology, Umifenovir, medicine.drug, Hepatitis C virus, medicine.disease_cause, Hepatitis B, Virus
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