publication . Article . 2012

Effects of Cinnamomum zeylanicum (Ceylon cinnamon) on blood glucose and lipids in a diabetic and healthy rat model

Priyanga Ranasinghe; Sanja Perera; Mangala Gunatilake; Eranga Abeywardene; Nuwan Gunapala; Sirimal Premakumara; Kamal Perera; Dilani Lokuhetty; Prasad Katulanda;
Open Access English
  • Published: 08 Apr 2012 Journal: Pharmacognosy Research, volume 4, issue 2, pages 73-79 (issn: 0976-4836, eissn: 0974-8490, Copyright policy)
  • Publisher: Medknow Publications & Media Pvt Ltd
Abstract
Objectives: To evaluate short- and long-term effects of Cinnamomum zeylanicum on food consumption, body weight, glycemic control, and lipids in healthy and diabetes-induced rats. Materials and Methods: The study was conducted in two phases (Phase I and Phase II), using Sprague-Dawley rats in four groups. Phase I evaluated acute effects on fasting blood glucose (FBG) (Groups 1 and 2) and on post-oral glucose (Groups 3 and 4) blood glucose. Groups 1 and 3 received distilled-water and Groups 2 and 4 received cinnamon-extracts. Phase II evaluated effects on food consumption, body weight, blood glucose, and lipids over 1 month. Group A (n = 8, distilled-water) and Gr...
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free text keywords: Original Article, Blood glucose, Ceylon cinnamon, Cinnamomum zeylanicum, diabetes mellitus, lipids, Sprague-Dawley rats, Drug Discovery, Pharmacology, Medicine, business.industry, business, Body weight, Diabetes mellitus, medicine.disease, Glycemic, Rat model, Sprague dawley rats, Traditional medicine, Food consumption, Cinnamomum zeylanicum
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