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Revista Brasileira de Reumatologia
Article . 2005 . Peer-reviewed
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Revista Brasileira de Reumatologia
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Consenso em reumatologia pediátrica: parte I - definição dos critérios de doença inativa e remissão em artrite idiopática juvenil/artrite reumatóide juvenil

Authors: Machado, Claudia; Ruperto, Nicolino;

Consenso em reumatologia pediátrica: parte I - definição dos critérios de doença inativa e remissão em artrite idiopática juvenil/artrite reumatóide juvenil

Abstract

Validated and widely accepted criteria for clinical remission in JIA/JRA do not currently exist. OBJECTIVE: To achieve consensus in this matter. METHODS: The Delphi consensus-formation approach was used to gather the criteria in use by pediatric rheumatologists (PR) worldwide. Results from the questionnaires provided the basis for the development of a consensus conference using the nominal group technique (NGT) to reach consensus on questions not solvable by the questionnaire format. One hundred and thirty PR from 34 countries responded the Delphi questionnaires and 20 PR from 9 countries attended a 2-day consensus conference. RESULTS: Consensus results were: criteria for inactive disease should include: 1) no active arthritis; 2) no fever, rash, serositis, splenomegaly, or generalised lymphadenopathy attributable to JIA/JRA; 3) no active uveitis; 4) normal ESR or CRP (if both are tested, both must be normal); 5) a physician's global assessment of disease activity rated at the best score possible and indicating no disease activity. CONCLUSIONS: According to consensus vote, 6 continuous months of inactive disease are necessary before classifying a patient as in remission on medication; 12 months off medication while maintaining inactive disease are necessary to classify a patient as in remission off medication. The criteria for in remission off medications should predict with 95% accuracy that a patient has a 20% probability of disease relapse within the next 5 years.

Keywords

remission, consensus, artrite reumatóide juvenil, juvenile rheumatoid arthritis, juvenile idiopathic arthritis, artrite idiopática juvenil, consenso, remissão

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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
7
Average
Top 10%
Average
Green
gold