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Genetics
Article . 2014 . Peer-reviewed
License: OUP Standard Publication Reuse
Data sources: Crossref
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Genetics
Article
Data sources: UnpayWall
Genetics
Article . 2014
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Large-Scale Mapping of Transposable Element Insertion Sites Using Digital Encoding of Sample Identity

Authors: Limor Freifeld; Limor Freifeld; Jennifer J. Hwa; Mark Horowitz; Daryl M. Gohl; Thomas R. Clandinin; Marion Silies;

Large-Scale Mapping of Transposable Element Insertion Sites Using Digital Encoding of Sample Identity

Abstract

Abstract Determining the genomic locations of transposable elements is a common experimental goal. When mapping large collections of transposon insertions, individualized amplification and sequencing is both time consuming and costly. We describe an approach in which large numbers of insertion lines can be simultaneously mapped in a single DNA sequencing reaction by using digital error-correcting codes to encode line identity in a unique set of barcoded pools.

Related Organizations
Keywords

Drosophila melanogaster, Genome, Insect, DNA Transposable Elements, Animals, Chromosome Mapping, High-Throughput Nucleotide Sequencing, Genomics, Sequence Analysis, DNA

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
hybrid