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R/qtl: QTL mapping in experimental crosses

Authors: Karl W, Broman; Hao, Wu; Saunak, Sen; Gary A, Churchill;

R/qtl: QTL mapping in experimental crosses

Abstract

Abstract Summary: R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by multiple methods, with the possible inclusion of covariates. Availability: The package is freely available at http://www.biostat.jhsph.edu/~kbroman/qtl. Contact: kbroman@jhsph.edu * To whom correspondence should be addressed. † Present address: Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143, USA.

Related Organizations
Subjects by Vocabulary

Microsoft Academic Graph classification: Quantitative trait locus Multiple methods Biology Genome Family-based QTL mapping Inbred strain Inclusive composite interval mapping Genotyping Genetics Genetic marker

Keywords

Genetic Markers, Statistics and Probability, Genotype, Quantitative Trait Loci, Biochemistry, Humans, Inbreeding, Molecular Biology, Crosses, Genetic, Genome, Models, Statistical, Models, Genetic, Gene Expression Profiling, Chromosome Mapping, Markov Chains, Computer Science Applications, Computational Mathematics, Computational Theory and Mathematics, Chromosomes, Human, Pair 1, Algorithms, Software

11 references, page 1 of 2

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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3K
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Top 0.1%
Top 0.1%
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