publication . Other literature type . Article . 2001

Anti-Gal-C antibodies in GBS subsequent to mycoplasma infection: Evidence of molecular mimicry

S. Kusunoki; M. Shiina; I. Kanazawa;
  • Published: 28 Aug 2001
  • Publisher: Ovid Technologies (Wolters Kluwer Health)
Abstract
The authors previously reported the presence of antibody against galactocerebroside (Gal-C) in sera from patients with Guillain–Barre syndrome subsequent to Mycoplasma pneumoniae infection. Anti-Gal-C antibody activities in these sera were inhibited specifically by the M. pneumoniae reagent. A rabbit anti-Gal-C antibody recognized several glycolipids in M. pneumoniae . These data show that a Gal-C-like structure is present in M. pneumoniae , indicative of molecular mimicry between a major myelin glycolipid, Gal-C, and M. pneumoniae .
Subjects
Medical Subject Headings: respiratory tract diseases
free text keywords: Clinical Neurology, Mycoplasma pneumoniae, medicine.disease_cause, medicine, Mollicutes, biology.organism_classification, biology, Virology, Mycoplasma, Molecular mimicry, Microbiology, Glycolipid, Galactocerebroside, Mycoplasmataceae, Antibody, biology.protein
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publication . Other literature type . Article . 2001

Anti-Gal-C antibodies in GBS subsequent to mycoplasma infection: Evidence of molecular mimicry

S. Kusunoki; M. Shiina; I. Kanazawa;