publication . Article . Other literature type . 2005

Molecular epidemiology of rabies in northern Colombia 1994-2003. Evidence for human and fox rabies associated with dogs

Páez, A.; Saad, C.; Núñez, C.; Bóshell, J.;
Open Access
  • Published: 01 Jun 2005 Journal: Epidemiology and Infection, volume 133, pages 529-536 (issn: 0950-2688, eissn: 1469-4409, Copyright policy)
  • Publisher: Cambridge University Press (CUP)
Abstract
<jats:p>During the period 2000–2003, wild grey foxes (<jats:italic>Urocyon cinereoargenteus</jats:italic>) in northern Colombia became infected with rabies. In order to derive phylogenetic relationships between rabies viruses isolated in foxes, dogs and humans in this region, 902 nt cDNA fragments containing the G–L intergenic region and encoding the cytoplasmic domain of protein G and a fragment of protein L were obtained by RT–PCR, sequenced and compared. Phylogenetic analysis showed that rabies viruses isolated in foxes, dogs and humans belonged to a single genetic variant. Speculative analysis together with epidemiological data indicated that rabies in foxes...
Subjects
Medical Subject Headings: parasitic diseasespopulation characteristicsgeographic locations
free text keywords: Epidemiology, Infectious Diseases, Biology, Genetic variants, Rabies transmission, Virology, Intergenic region, Phylogenetic tree, Rabies, medicine.disease, medicine, Molecular epidemiology, Urocyon, biology.organism_classification, Research Article
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