publication . Other literature type . Article . 2015

Fabrication and characterization of conductive chitosan/gelatin-based scaffolds for nerve tissue engineering.

Ahmad Ramazani S.A; Hossein Baniasadi; Shohreh Mashayekhan;
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  • Published: 01 Mar 2015
  • Publisher: Elsevier BV
Abstract
This paper reports on the development of conductive porous scaffolds by incorporating conductive polyaniline/graphene (PAG) nanoparticles into a chitosan/gelatin matrix for its potential application in peripheral nerve regeneration. The effect of PAG content on the various properties of the scaffold is investigated and the results showed that the electrical conductivity and mechanical properties increased proportional to the increase in the PAG loading, while the porosity, swelling ratio and in vitro biodegradability decreased. In addition, the biocompatibility was evaluated by assessing the adhesion and proliferation of Schwann cells on the prepared scaffolds u...
Subjects
Medical Subject Headings: nervous system
free text keywords: Adhesion, Tissue engineering, Chitosan, chemistry.chemical_compound, chemistry, Biomedical engineering, Gelatin, food.ingredient, food, Biocompatibility, Nanoparticle, Materials science, Scaffold, Polyaniline
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