publication . Other literature type . Article . 2002

White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging

Bozzali, M; Falini, A; Franceschi, M; Cercignani, M; Zuffi, M; Scotti, G; Comi, G; Filippi, M;
Open Access English
  • Published: 01 Jun 2002
  • Publisher: BMJ Group
Abstract
Objective: To investigate the extent and the nature of white matter tissue damage of patients with Alzheimer's disease using diffusion tensor magnetic resonance imaging (DT-MRI). Background: Although Alzheimer's disease pathology mainly affects cortical grey matter, previous pathological and MRI studies showed that also the brain white matter of patients is damaged. However, the nature of Alzheimer's disease associated white matter damage is still unclear. Methods: Conventional and DT-MRI scans were obtained from16 patients with Alzheimer's disease and 10 sex and age matched healthy volunteers. The mean diffusivity (), fractional anisotropy (FA), and inter-voxel...
Subjects
free text keywords: Paper, Dementia, medicine.disease, medicine, Internal capsule, Fractional anisotropy, business.industry, business, Corpus callosum, Pathology, medicine.medical_specialty, Grey matter, medicine.anatomical_structure, Magnetic resonance imaging, medicine.diagnostic_test, Alzheimer's disease, White matter
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publication . Other literature type . Article . 2002

White matter damage in Alzheimer's disease assessed in vivo using diffusion tensor magnetic resonance imaging

Bozzali, M; Falini, A; Franceschi, M; Cercignani, M; Zuffi, M; Scotti, G; Comi, G; Filippi, M;