publication . Other literature type . Article . 1992

Erratum: Atomic structure and chemistry of human serum albumin

Xiao Min He; Daniel C. Carter;
Open Access
  • Published: 16 Jul 1992
  • Publisher: Springer Nature
Abstract
The three-dimensional structure of human serum albumin has been determined crystallographically to a resolution of 2.8 A. It comprises three homologous domains that assemble to form a heart-shaped molecule. Each domain is a product of two subdomains that possess common structural motifs. The principal regions of ligand binding to human serum albumin are located in hydrophobic cavities in subdomains IIA and IIIA, which exhibit similar chemistry. The structure explains numerous physical phenomena and should provide insight into future pharmacokinetic and genetically engineered therapeutic applications of serum albumin.
Subjects
free text keywords: Multidisciplinary
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ZENODO
Article . 1992
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Nature
Article
Provider: UnpayWall
Abstract
The three-dimensional structure of human serum albumin has been determined crystallographically to a resolution of 2.8 A. It comprises three homologous domains that assemble to form a heart-shaped molecule. Each domain is a product of two subdomains that possess common structural motifs. The principal regions of ligand binding to human serum albumin are located in hydrophobic cavities in subdomains IIA and IIIA, which exhibit similar chemistry. The structure explains numerous physical phenomena and should provide insight into future pharmacokinetic and genetically engineered therapeutic applications of serum albumin.
Subjects
free text keywords: Multidisciplinary
Download fromView all 6 versions
Nature
Article
Provider: UnpayWall
ZENODO
Article . 1992
Provider: ZENODO
Nature
Article
Provider: UnpayWall
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