publication . Article . Other literature type . 2014

Interplay Between Plasmodium Infection and Resistance to Insecticides in Vector Mosquitoes

Alout, Haoues; Yameogo, Bienvenue; Djogbenou, Luc Salako; Chandre, Fabrice; Dabiré, Roch Kounbobr; Corbel, Vincent; Cohuet, Anna;
Open Access English
  • Published: 14 May 2014
  • Publisher: HAL CCSD
  • Country: United States
Abstract
Despite its epidemiological importance, the impact of insecticide resistance on vector-parasite interactions and malaria transmission is poorly understood. Here, we explored the impact of Plasmodium infection on the level of insecticide resistance to dichlorodiphenyltrichloroethane (DDT) in field-caught Anopheles gambiae sensu stricto homozygous for the kdr mutation. Results showed that kdr homozygous mosquitoes that fed on infectious blood were more susceptible to DDT than mosquitoes that fed on noninfectious blood during both ookinete development (day 1 after the blood meal) and oocyst maturation (day 7 after the blood meal) but not during sporozoite invasion ...
Subjects
Medical Subject Headings: parasitic diseasesgeographic locations
free text keywords: malaria, cost of infection, Anopheles gambiae, insecticide exposure, kdr, insecticide resistance, Plasmodium falciparum, [SDV]Life Sciences [q-bio], Immunology and Allergy, Infectious Diseases, Virology, DDT (Insecticide), biology.organism_classification, biology, medicine.disease, medicine, Anopheles, business.industry, business
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