publication . Article . 2012

Targeted Ultrasound Imaging of Cancer: An Emerging Technology on its Way to Clinics

Kiessling, Fabian; Bzyl, Jessica; Fokong, Stanley; Siepmann, Monica; Georg Schmitz; Palmowski, Moritz;
  • Published: 01 Mar 2012 Journal: Current Pharmaceutical Design, volume 18, pages 2,184-2,199 (issn: 1381-6128, Copyright policy)
  • Publisher: Bentham Science Publishers Ltd.
Ultrasound is one of the workhorses in clinical cancer diagnosis. In particular, it is routinely used to characterize lesions inliver, urogenital tract, head and neck and soft tissues. During the last years image quality steadily improved, which, among others, can beattributed to the development of harmonic image analysis. Microbubbles were introduced as intravascular contrast agents and can be detectedwith superb sensitivity and specificity using contrast specific imaging modes. By aid of these unspecific contrast agents tissues canbe characterised regarding their vascularity. Antibodies, peptides and other targeting moieties were bound to microbubbles to targe...
free text keywords: Pharmacology, Drug Discovery, Medicine, business.industry, business, Microbubbles, Clinical reality, Medical physics, medicine.medical_specialty, Therapy response, Cancer, medicine.disease, Ultrasound imaging, Ultrasound
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