research data . Dataset . 2019

Her2-Functionalized Gold-Nanoshelled Magnetic Hybrid Nanoparticles: a Theranostic Agent for Dual-Modal Imaging and Photothermal Therapy of Breast Cancer

Dong, Qi; Yang, Hong; Caifeng Wan; Dongdong Zheng; Zhiguo Zhou; Shaowei Xie; Xu, Li; Du, Jing; Fenghua Li;
  • Published: 26 Aug 2019
  • Publisher: Springer Science and Business Media LLC
Abstract
Abstract Targeted theranostic platform that integrates multi-modal imaging and therapeutic function is emerging as a promising strategy for earlier detection and precise treatment of cancer. Herein, we designed targeted gold-nanoshelled poly (lactic-co-glycolic acid) (PLGA) magnetic hybrid nanoparticles carrying anti-human epidermal growth factor receptor 2 (Her2) antibodies (Her2-GPH NPs) for dual-modal ultrasound (US)/magnetic resonance (MR) imaging and photothermal therapy of breast cancer. The agent was
Subjects
free text keywords: Biophysics, Biochemistry, Space Science, Medicine, Cell Biology, Molecular Biology, Biotechnology, 39999 Chemical Sciences not elsewhere classified, Cancer
Abstract
Abstract Targeted theranostic platform that integrates multi-modal imaging and therapeutic function is emerging as a promising strategy for earlier detection and precise treatment of cancer. Herein, we designed targeted gold-nanoshelled poly (lactic-co-glycolic acid) (PLGA) magnetic hybrid nanoparticles carrying anti-human epidermal growth factor receptor 2 (Her2) antibodies (Her2-GPH NPs) for dual-modal ultrasound (US)/magnetic resonance (MR) imaging and photothermal therapy of breast cancer. The agent was
Subjects
free text keywords: Biophysics, Biochemistry, Space Science, Medicine, Cell Biology, Molecular Biology, Biotechnology, 39999 Chemical Sciences not elsewhere classified, Cancer
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