publication . Article . Other literature type . 2009

Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women.

Alfredo Mayor; Alfredo Mayor; Azucena Bardají; Azucena Bardají; John J. Aponte; John J. Aponte; Pedro L. Alonso; Pedro L. Alonso; Pau Cisteró; Betuel Sigaúque; ...
Open Access
  • Published: 09 Jan 2009
  • Publisher: Springer Science and Business Media LLC
Abstract
<p>Abstract</p> <p>Background</p> <p>Control of malaria in pregnancy remains a public health challenge. Improvements in its correct diagnosis and the adequacy of protocols to evaluate anti-malarial drug efficacy in pregnancy, are essential to achieve this goal.</p> <p>Methods</p> <p>The presence of <it>Plasmodium falciparum </it>was assessed by real-time (RT) PCR in 284 blood samples from pregnant women with clinical complaints suggestive of malaria, attending the maternity clinic of a Mozambican rural hospital. Parasite recrudescences in 33 consecutive paired episodes during the same pregnancy were identified by <it>msp1 </it>and <it>msp2 </it>genotyping.</p> <...
Subjects
Medical Subject Headings: parasitic diseases
free text keywords: Research, Parasitology, Infectious Diseases, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216, Sulfadoxine, medicine.medical_treatment, medicine, Pregnancy, medicine.disease, Pediatrics, medicine.medical_specialty, Chloroquine, medicine.drug, Immunology, Biology, Public health, Plasmodium falciparum, biology.organism_classification, Malaria, Pyrimethamine, Efficacy
Related Organizations
42 references, page 1 of 3

Diagne, N, Rogier, C, Cisse, B, Trape, JF. Incidence of clinical malaria in pregnant women exposed to intense perennial transmission. Trans R Soc Trop Med Hyg. 1997; 91: 166-170 [OpenAIRE] [PubMed] [DOI]

Menendez, C, Ordi, J, Ismail, MR, Ventura, PJ, Aponte, JJ, Kahigwa, E, Font, F, Alonso, PL. The impact of placental malaria on gestational age and birth weight. J Infect Dis. 2000; 181: 1740-1745 [OpenAIRE] [PubMed] [DOI]

Brabin, B, Prinsen-Geerligs, P, Verhoeff, F, Kazembe, P. Anaemia prevention for reduction of mortality in mothers and children. Trans R Soc Trop Med Hyg. 2003; 97: 36-38 [OpenAIRE] [PubMed] [DOI]

A strategic framework for malaria prevention and control during pregnancy in the African region. 2004

Steketee, RW, Wirima, JJ, Slutsker, L, Khoromana, CO, Heymann, DL, Breman, JG. Malaria treatment and prevention in pregnancy: indications for use and adverse events associated with use of chloroquine or mefloquine. Am J Trop Med Hyg. 1996; 55: 50-56 [OpenAIRE] [PubMed]

Bardaji, A, Sigauque, B, Romagosa, C, Bruni, L, Sanz, S, Mabunda, S, Mandomando, I, Aponte, J, Sevene, E, Alonso, PL, Menendez, C. Clinical malaria in African pregnant women. Malar J. 2008; 7: 27 [OpenAIRE] [PubMed] [DOI]

Moody, A. Rapid diagnostic tests for malaria parasites. Clin Microbiol Rev. 2002; 15: 66-78 [OpenAIRE] [PubMed] [DOI]

Mockenhaupt, FP, Rong, B, Till, H, Eggelte, TA, Beck, S, Gyasi-Sarpong, C, Thompson, WN, Bienzle, U. Submicroscopic Plasmodium falciparum infections in pregnancy in Ghana. Trop Med Int Health. 2000; 5: 167-173 [OpenAIRE] [PubMed] [DOI]

Schleiermacher, D, Rogier, C, Spiegel, A, Tall, A, Trape, JF, Mercereau-Puijalon, O. Increased multiplicity of Plasmodium falciparum infections and skewed distribution of individual msp1 and msp2 alleles during pregnancy in Ndiop, a Senegalese village with seasonal, mesoendemic malaria. Am J Trop Med Hyg. 2001; 64: 303-309 [PubMed]

Saute, F, Menendez, C, Mayor, A, Aponte, J, Gomez-Olive, X, Dgedge, M, Alonso, P. Malaria in pregnancy in rural Mozambique: the role of parity, submicroscopic and multiple Plasmodium falciparum infections. Trop Med Int Health. 2002; 7: 19-28 [OpenAIRE] [PubMed] [DOI]

Mayengue, PI, Rieth, H, Khattab, A, Issifou, S, Kremsner, PG, Klinkert, MQ, Ntoumi, F. Submicroscopic Plasmodium falciparum infections and multiplicity of infection in matched peripheral, placental and umbilical cord blood samples from Gabonese women. Trop Med Int Health. 2004; 9: 949-958 [OpenAIRE] [PubMed] [DOI]

Walker-Abbey, A, Djokam, RR, Eno, A, Leke, RF, Titanji, VP, Fogako, J, Sama, G, Thuita, LH, Beardslee, E, Snounou, G, Zhou, A, Taylor, DW. Malaria in pregnant Cameroonian women: the effect of age and gravidity on submicroscopic and mixed-species infections and multiple parasite genotypes. Am J Trop Med Hyg. 2005; 72: 229-235 [PubMed]

Hermsen, CC, Telgt, DS, Linders, EH, Locht, LA van de, Eling, WM, Mensink, EJ, Sauerwein, RW. Detection of Plasmodium falciparum malaria parasites in vivo by real-time quantitative PCR. Mol Biochem Parasitol. 2001; 118: 247-251 [OpenAIRE] [PubMed] [DOI]

Hermsen, CC, de Vlas, SJ, van Gemert, GJ, Telgt, DS, Verhage, DF, Sauerwein, RW. Testing vaccines in human experimental malaria: statistical analysis of parasitemia measured by a quantitative real-time polymerase chain reaction. Am J Trop Med Hyg. 2004; 71: 196-201 [PubMed]

Malhotra, I, Dent, A, Mungai, P, Muchiri, E, King, CL. Real-time quantitative PCR for determining the burden of Plasmodium falciparum parasites during pregnancy and infancy. J Clin Microbiol. 2005; 43: 3630-3635 [OpenAIRE] [PubMed] [DOI]

42 references, page 1 of 3
Abstract
<p>Abstract</p> <p>Background</p> <p>Control of malaria in pregnancy remains a public health challenge. Improvements in its correct diagnosis and the adequacy of protocols to evaluate anti-malarial drug efficacy in pregnancy, are essential to achieve this goal.</p> <p>Methods</p> <p>The presence of <it>Plasmodium falciparum </it>was assessed by real-time (RT) PCR in 284 blood samples from pregnant women with clinical complaints suggestive of malaria, attending the maternity clinic of a Mozambican rural hospital. Parasite recrudescences in 33 consecutive paired episodes during the same pregnancy were identified by <it>msp1 </it>and <it>msp2 </it>genotyping.</p> <...
Subjects
Medical Subject Headings: parasitic diseases
free text keywords: Research, Parasitology, Infectious Diseases, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216, Sulfadoxine, medicine.medical_treatment, medicine, Pregnancy, medicine.disease, Pediatrics, medicine.medical_specialty, Chloroquine, medicine.drug, Immunology, Biology, Public health, Plasmodium falciparum, biology.organism_classification, Malaria, Pyrimethamine, Efficacy
Related Organizations
42 references, page 1 of 3

Diagne, N, Rogier, C, Cisse, B, Trape, JF. Incidence of clinical malaria in pregnant women exposed to intense perennial transmission. Trans R Soc Trop Med Hyg. 1997; 91: 166-170 [OpenAIRE] [PubMed] [DOI]

Menendez, C, Ordi, J, Ismail, MR, Ventura, PJ, Aponte, JJ, Kahigwa, E, Font, F, Alonso, PL. The impact of placental malaria on gestational age and birth weight. J Infect Dis. 2000; 181: 1740-1745 [OpenAIRE] [PubMed] [DOI]

Brabin, B, Prinsen-Geerligs, P, Verhoeff, F, Kazembe, P. Anaemia prevention for reduction of mortality in mothers and children. Trans R Soc Trop Med Hyg. 2003; 97: 36-38 [OpenAIRE] [PubMed] [DOI]

A strategic framework for malaria prevention and control during pregnancy in the African region. 2004

Steketee, RW, Wirima, JJ, Slutsker, L, Khoromana, CO, Heymann, DL, Breman, JG. Malaria treatment and prevention in pregnancy: indications for use and adverse events associated with use of chloroquine or mefloquine. Am J Trop Med Hyg. 1996; 55: 50-56 [OpenAIRE] [PubMed]

Bardaji, A, Sigauque, B, Romagosa, C, Bruni, L, Sanz, S, Mabunda, S, Mandomando, I, Aponte, J, Sevene, E, Alonso, PL, Menendez, C. Clinical malaria in African pregnant women. Malar J. 2008; 7: 27 [OpenAIRE] [PubMed] [DOI]

Moody, A. Rapid diagnostic tests for malaria parasites. Clin Microbiol Rev. 2002; 15: 66-78 [OpenAIRE] [PubMed] [DOI]

Mockenhaupt, FP, Rong, B, Till, H, Eggelte, TA, Beck, S, Gyasi-Sarpong, C, Thompson, WN, Bienzle, U. Submicroscopic Plasmodium falciparum infections in pregnancy in Ghana. Trop Med Int Health. 2000; 5: 167-173 [OpenAIRE] [PubMed] [DOI]

Schleiermacher, D, Rogier, C, Spiegel, A, Tall, A, Trape, JF, Mercereau-Puijalon, O. Increased multiplicity of Plasmodium falciparum infections and skewed distribution of individual msp1 and msp2 alleles during pregnancy in Ndiop, a Senegalese village with seasonal, mesoendemic malaria. Am J Trop Med Hyg. 2001; 64: 303-309 [PubMed]

Saute, F, Menendez, C, Mayor, A, Aponte, J, Gomez-Olive, X, Dgedge, M, Alonso, P. Malaria in pregnancy in rural Mozambique: the role of parity, submicroscopic and multiple Plasmodium falciparum infections. Trop Med Int Health. 2002; 7: 19-28 [OpenAIRE] [PubMed] [DOI]

Mayengue, PI, Rieth, H, Khattab, A, Issifou, S, Kremsner, PG, Klinkert, MQ, Ntoumi, F. Submicroscopic Plasmodium falciparum infections and multiplicity of infection in matched peripheral, placental and umbilical cord blood samples from Gabonese women. Trop Med Int Health. 2004; 9: 949-958 [OpenAIRE] [PubMed] [DOI]

Walker-Abbey, A, Djokam, RR, Eno, A, Leke, RF, Titanji, VP, Fogako, J, Sama, G, Thuita, LH, Beardslee, E, Snounou, G, Zhou, A, Taylor, DW. Malaria in pregnant Cameroonian women: the effect of age and gravidity on submicroscopic and mixed-species infections and multiple parasite genotypes. Am J Trop Med Hyg. 2005; 72: 229-235 [PubMed]

Hermsen, CC, Telgt, DS, Linders, EH, Locht, LA van de, Eling, WM, Mensink, EJ, Sauerwein, RW. Detection of Plasmodium falciparum malaria parasites in vivo by real-time quantitative PCR. Mol Biochem Parasitol. 2001; 118: 247-251 [OpenAIRE] [PubMed] [DOI]

Hermsen, CC, de Vlas, SJ, van Gemert, GJ, Telgt, DS, Verhage, DF, Sauerwein, RW. Testing vaccines in human experimental malaria: statistical analysis of parasitemia measured by a quantitative real-time polymerase chain reaction. Am J Trop Med Hyg. 2004; 71: 196-201 [PubMed]

Malhotra, I, Dent, A, Mungai, P, Muchiri, E, King, CL. Real-time quantitative PCR for determining the burden of Plasmodium falciparum parasites during pregnancy and infancy. J Clin Microbiol. 2005; 43: 3630-3635 [OpenAIRE] [PubMed] [DOI]

42 references, page 1 of 3
Any information missing or wrong?Report an Issue