publication . Article . Other literature type . 2003

Synthetic methyl hexagalacturonate hapten inhibitors of anti-homogalacturonan monoclonal antibodies LM7, JIM5 and JIM7

Clausen, Mads H.; Willats, William G.T.; Knox, J.Paul;
  • Published: 01 Aug 2003 Journal: Carbohydrate Research, volume 338, pages 1,797-1,800 (issn: 0008-6215, Copyright policy)
  • Publisher: Elsevier BV
A range of synthetic methyl hexagalacturonates were used as potential hapten inhibitors in competitive-inhibition enzyme-linked immunosorbent assays (ELISAs) with anti-homogalacturonan monoclonal antibodies LM7, JIM5 and JIM7. The selective inhibition of these antibodies by different haptens provides insight into the structures of the partially methyl-esterified pectin epitopes of these widely used monoclonal antibodies.
free text keywords: Organic Chemistry, Analytical Chemistry, Biochemistry, General Medicine, Biology, Monoclonal antibody, medicine.drug_class, medicine, Antibody, biology.protein, Epitope, Hapten, Selective inhibition
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