publication . Article . Other literature type . 2013

Endosymbiosis in trypanosomatids: the genomic cooperation between bacterium and host in the synthesis of essential amino acids is heavily influenced by multiple horizontal gene transfers

Myrna G. Serrano; Gregory A. Buck; Maria Cristina M. Motta; Cecilia Coimbra Klein; Cecilia Coimbra Klein; André G. Costa-Martins; Ana Tereza Ribeiro de Vasconcelos; Marie-France Sagot; Marie-France Sagot; João M. P. Alves; ...
Open Access English
  • Published: 01 Sep 2013 Journal: BMC Evolutionary Biology, volume 13, pages 190-190 (eissn: 1471-2148, Copyright policy)
  • Publisher: BioMed Central
  • Country: France
Abstract
International audience; Background<br />Trypanosomatids of the genera Angomonas and Strigomonas live in a mutualistic association characterized by extensive metabolic cooperation with obligate endosymbiotic Betaproteobacteria. However, the role played by the symbiont has been more guessed by indirect means than evidenced. Symbiont-harboring trypanosomatids, in contrast to their counterparts lacking symbionts, exhibit lower nutritional requirements and are autotrophic for essential amino acids. To evidence the symbiont's contributions to this autotrophy, entire genomes of symbionts and trypanosomatids with and without symbionts were sequenced here.<br />Results<b...
Subjects
Medical Subject Headings: fungibiochemical phenomena, metabolism, and nutritionparasitic diseases
free text keywords: Research Article, Endosymbiosis, Trypanosomatids, Amino acid biosynthesis, Phylogeny, Genomic analyses, Metabolic pathway evolution, Proteobacteria, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, [SDV.SA]Life Sciences [q-bio]/Agricultural sciences, Ecology, Evolution, Behavior and Systematics, Botany, Amino acid synthesis, chemistry.chemical_classification, chemistry, Biology, biology.organism_classification, Phylogenetics, Symbiosis, Genetics, Obligate, Genome, Betaproteobacteria
Funded by
NSF| Assembling the Tree of Life: Phylum Euglenozoa
Project
  • Funder: National Science Foundation (NSF)
  • Project Code: 0830056
  • Funding stream: Directorate for Biological Sciences | Division of Environmental Biology
,
EC| SISYPHE
Project
SISYPHE
Species Identity and SYmbiosis Formally and Experimentally explored
  • Funder: European Commission (EC)
  • Project Code: 247073
  • Funding stream: FP7 | SP2 | ERC
93 references, page 1 of 7

1. Baumann P, Moran NA, Baumann L: The evolution and genetics of aphid endosymbionts. BioScience 1997, 47:12-20.

2. Wernegreen JJ: Genome evolution in bacterial endosymbionts of insects. Nat Rev Genet 2002, 3:850-861. [OpenAIRE]

3. Wernegreen JJ: Endosymbiosis: lessons in conflict resolution. PLoS Biol 2004, 2:E68.

4. Moran NA: Symbiosis. Curr Biol 2006, 16:R866-R871.

5. Moran NA, McCutcheon JP, Nakabachi A: Genomics and evolution of heritable bacterial symbionts. Annu Rev Genet 2008, 42:165-190. [OpenAIRE]

6. Wernegreen JJ: Strategies of genomic integration within insect-bacterial mutualisms. Biol Bull 2012, 223:112-122. [OpenAIRE]

7. McCutcheon JP, von Dohlen CD: An interdependent metabolic patchwork in the nested symbiosis of mealybugs. Curr Biol 2011, 21:1366-1372. [OpenAIRE]

8. Horn M, Wagner M: Bacterial endosymbionts of free-living amoebae. J Eukaryot Microbiol 2004, 51:509-514.

9. Heinz E, Kolarov I, Kästner C, Toenshoff ER, Wagner M, Horn M: An Acanthamoeba sp. containing two phylogenetically different bacterial endosymbionts. Environ Microbiol 2007, 9:1604-1609. [OpenAIRE]

10. Nowack ECM, Melkonian M: Endosymbiotic associations within protists. Philos Trans R Soc Lond B Biol Sci 2010, 365:699-712. [OpenAIRE]

11. Chang KP, Chang CS, Sassa S: Heme biosynthesis in bacterium-protozoon symbioses: enzymic defects in host hemoflagellates and complemental role of their intracellular symbiotes. Proc Natl Acad Sci USA 1975, 72:2979-2983. [OpenAIRE]

12. Roitman I, Camargo EP: Endosymbionts of trypanosomatidae. Parasitol Today (Regul. Ed.) 1985, 1:143-144.

13. Du Y, Maslov DA, Chang KP: Monophyletic origin of beta-division proteobacterial endosymbionts and their coevolution with insect trypanosomatid protozoa Blastocrithidia culicis and Crithidia spp. Proc Natl Acad Sci USA 1994, 91:8437-8441.

14. Motta MCM, Catta-Preta CMC, Schenkman S, De Azevedo Martins AC, Miranda K, De Souza W, Elias MC: The bacterium endosymbiont of Crithidia deanei undergoes coordinated division with the host cell nucleus. PLoS ONE 2010, 5:e12415. [OpenAIRE]

15. Hoare CA: Herpetosoma from man and other mammals. In The Trypanosomes of Mammals: A Zoological Monograph. Oxford: Blackwell Scientific Publications; 1972:288-314.

93 references, page 1 of 7
Abstract
International audience; Background<br />Trypanosomatids of the genera Angomonas and Strigomonas live in a mutualistic association characterized by extensive metabolic cooperation with obligate endosymbiotic Betaproteobacteria. However, the role played by the symbiont has been more guessed by indirect means than evidenced. Symbiont-harboring trypanosomatids, in contrast to their counterparts lacking symbionts, exhibit lower nutritional requirements and are autotrophic for essential amino acids. To evidence the symbiont's contributions to this autotrophy, entire genomes of symbionts and trypanosomatids with and without symbionts were sequenced here.<br />Results<b...
Subjects
Medical Subject Headings: fungibiochemical phenomena, metabolism, and nutritionparasitic diseases
free text keywords: Research Article, Endosymbiosis, Trypanosomatids, Amino acid biosynthesis, Phylogeny, Genomic analyses, Metabolic pathway evolution, Proteobacteria, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, [SDV.SA]Life Sciences [q-bio]/Agricultural sciences, Ecology, Evolution, Behavior and Systematics, Botany, Amino acid synthesis, chemistry.chemical_classification, chemistry, Biology, biology.organism_classification, Phylogenetics, Symbiosis, Genetics, Obligate, Genome, Betaproteobacteria
Funded by
NSF| Assembling the Tree of Life: Phylum Euglenozoa
Project
  • Funder: National Science Foundation (NSF)
  • Project Code: 0830056
  • Funding stream: Directorate for Biological Sciences | Division of Environmental Biology
,
EC| SISYPHE
Project
SISYPHE
Species Identity and SYmbiosis Formally and Experimentally explored
  • Funder: European Commission (EC)
  • Project Code: 247073
  • Funding stream: FP7 | SP2 | ERC
93 references, page 1 of 7

1. Baumann P, Moran NA, Baumann L: The evolution and genetics of aphid endosymbionts. BioScience 1997, 47:12-20.

2. Wernegreen JJ: Genome evolution in bacterial endosymbionts of insects. Nat Rev Genet 2002, 3:850-861. [OpenAIRE]

3. Wernegreen JJ: Endosymbiosis: lessons in conflict resolution. PLoS Biol 2004, 2:E68.

4. Moran NA: Symbiosis. Curr Biol 2006, 16:R866-R871.

5. Moran NA, McCutcheon JP, Nakabachi A: Genomics and evolution of heritable bacterial symbionts. Annu Rev Genet 2008, 42:165-190. [OpenAIRE]

6. Wernegreen JJ: Strategies of genomic integration within insect-bacterial mutualisms. Biol Bull 2012, 223:112-122. [OpenAIRE]

7. McCutcheon JP, von Dohlen CD: An interdependent metabolic patchwork in the nested symbiosis of mealybugs. Curr Biol 2011, 21:1366-1372. [OpenAIRE]

8. Horn M, Wagner M: Bacterial endosymbionts of free-living amoebae. J Eukaryot Microbiol 2004, 51:509-514.

9. Heinz E, Kolarov I, Kästner C, Toenshoff ER, Wagner M, Horn M: An Acanthamoeba sp. containing two phylogenetically different bacterial endosymbionts. Environ Microbiol 2007, 9:1604-1609. [OpenAIRE]

10. Nowack ECM, Melkonian M: Endosymbiotic associations within protists. Philos Trans R Soc Lond B Biol Sci 2010, 365:699-712. [OpenAIRE]

11. Chang KP, Chang CS, Sassa S: Heme biosynthesis in bacterium-protozoon symbioses: enzymic defects in host hemoflagellates and complemental role of their intracellular symbiotes. Proc Natl Acad Sci USA 1975, 72:2979-2983. [OpenAIRE]

12. Roitman I, Camargo EP: Endosymbionts of trypanosomatidae. Parasitol Today (Regul. Ed.) 1985, 1:143-144.

13. Du Y, Maslov DA, Chang KP: Monophyletic origin of beta-division proteobacterial endosymbionts and their coevolution with insect trypanosomatid protozoa Blastocrithidia culicis and Crithidia spp. Proc Natl Acad Sci USA 1994, 91:8437-8441.

14. Motta MCM, Catta-Preta CMC, Schenkman S, De Azevedo Martins AC, Miranda K, De Souza W, Elias MC: The bacterium endosymbiont of Crithidia deanei undergoes coordinated division with the host cell nucleus. PLoS ONE 2010, 5:e12415. [OpenAIRE]

15. Hoare CA: Herpetosoma from man and other mammals. In The Trypanosomes of Mammals: A Zoological Monograph. Oxford: Blackwell Scientific Publications; 1972:288-314.

93 references, page 1 of 7
Any information missing or wrong?Report an Issue