publication . Article . Other literature type . 1981

Urinary-excretion of Inorganic Arsenic and its Metabolites After Repeated Ingestion of Sodium Metaarsenite By Volunteers

Buchet, J. P.; Lauwerys, R.; Roels, H.;
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  • Published: 01 May 1981 Journal: International Archives of Occupational and Environmental Health, volume 48, pages 111-118 (issn: 0340-0131, eissn: 1432-1246, Copyright policy)
  • Publisher: Springer Nature
Abstract
Arsenic (125, 250, 500 or 1000 μg as NaAsO2) was administered orally once a day for five consecutive days to 4 volunteers who refrained from eating marine organisms during the experiment. Urine was collected during 24-h periods starting one day before the first administration and up to 14 days later. The following determinations were performed: total arsenic, inorganic arsenic (As;), monomethyl arsenic (MMA) and dimethylarsinic (DMA) acids. In each case, the sum of As;, MMA and DMA approximated very closely the urinary concentration of total arsenic determined after mineralisation of the urine sample. It was concluded that these arsenicals are the only metabolic...
Subjects
Medical Subject Headings: inorganic chemicalsintegumentary system
free text keywords: Public Health, Environmental and Occupational Health, Ingestion, Biological half-life, Organic chemistry, Urinary excretion, Chemistry, Urine, Arsenic, chemistry.chemical_element, Inorganic arsenic, Environmental chemistry, Chromatography, Urinary concentration, Creatinine, chemistry.chemical_compound
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