publication . Other literature type . Article . 2015

Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care

Ian J. Douglas; Krishnan Bhaskaran; Rachel L. Batterham; Liam Smeeth;
  • Published: 22 Dec 2015
  • Publisher: Public Library of Science (PLoS)
  • Country: United Kingdom
Abstract
Background Bariatric surgery is becoming a more widespread treatment for obesity. Comprehensive evidence of the long-term effects of contemporary surgery on a broad range of clinical outcomes in large populations treated in routine clinical practice is lacking. The objective of this study was to measure the association between bariatric surgery, weight, body mass index, and obesity-related co-morbidities. Methods and Findings This was an observational retrospective cohort study using data from the United Kingdom Clinical Practice Research Datalink. All 3,882 patients registered in the database and with bariatric surgery on or before 31 December 2014 were include...
Subjects
free text keywords: Research Article, Medicine, R, General Medicine, Weight loss, medicine.symptom, Surgery, medicine.medical_specialty, Retrospective cohort study, Sleeve gastrectomy, medicine.medical_treatment, Obesity, medicine.disease, Population, education.field_of_study, education, Type 2 diabetes, business.industry, business, Body mass index, Cohort study
46 references, page 1 of 4

1. Department of Health. Obesity general information. 1 February 2011. Available: http://webarchive. nationalarchives.gov.uk/+/www.dh.gov.uk/en/Publichealth/Obesity/DH_078098. Accessed 8 May 2015.

2. World Health Organization. Obesity and overweight. Fact sheet no. 311. January 2015. Available: http://www.who.int/mediacentre/factsheets/fs311/en/index.html. Accessed 8 May 2015.

3. National Institute for Health and Care Excellence. Obesity prevention. NICE guidelines CG43. December 2006. Available: http://guidance.nice.org.uk/CG43. Accessed 8 May 2015.

4. National Health Service Commissioning Board. Clinical commissioning policy: complex and specialised obesity surgery. April 2013. NHSCB/A05/P/a. Available: https://www.england.nhs.uk/wp-content/ uploads/2013/04/a05-p-a.pdf. Accessed 20 November 2015.

5. National Heart, Lung, and Blood Institute Obesity Education Initiative Expert Panel on the Identification, Evaluation, and Treatment of Obesity in Adults. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report. Report No. 98-4083. Bethesda (Maryland): National Heart, Lung, and Blood Institute; 1998.

6. National Institute for Health and Care Excellence. Obesity: identification, assessment and management. NICE guidelines CG189. November 2014. Available: http://www.nice.org.uk/guidance/cg189. Accessed 15 May 2015.

7. Courcoulas AP, Goodpaster BH, Eagleton JK, Belle SH, Kalarchian MA, Lang W, et al. Surgical vs medical treatments for type 2 diabetes mellitus: a randomized clinical trial. JAMA Surg. 2014; 149:707- 715. doi: 10.1001/jamasurg.2014.467 PMID: 24899268 [OpenAIRE]

8. O'Brien PE, Brennan L, Laurie C, Brown W. Intensive medical weight loss or laparoscopic adjustable gastric banding in the treatment of mild to moderate obesity: long-term follow-up of a prospective randomised trial. Obes Surg. 2013 23:1345-1353. doi: 10.1007/s11695-013-0990-3 PMID: 23760764

9. Schauer PR, Kashyap SR, Wolski K, Brethauer SA, Kirwan JP, Pothier CE, et al. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med. 2012; 366:1567-1576. doi: 10.1056/NEJMoa1200225 PMID: 22449319

10. Mingrone G, Panunzi S, De Gaetano A, Guidone C, Iaconelli A, Leccesi L, et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med. 2012; 366:1577-1585. doi: 10. 1056/NEJMoa1200111 PMID: 22449317

11. Campbell J, Dedman DJ, Eaton SC, Gallagher AM, Williams TJ. Is the CPRD GOLD population comparable to the U.K. population? Pharmacoepidemiol Drug Saf 2013; 22(Suppl 1):280.

12. Herrett E, Thomas SL, Schoonen WM, Smeeth L, Hall AJ. Validation and validity of diagnoses in the General Practice Research Database: a systematic review. Br J Clin Pharmacol. 2010; 69:4-14. doi: 10.1111/j.1365-2125.2009.03537.x PMID: 20078607 [OpenAIRE]

13. Bhaskaran K, Forbes H, Douglas I, Leon D, Smeeth L. Representativeness and optimal use of body mass index (BMI) in the UK Clinical Practice Research Datalink (CPRD). BMJ Open 2013; 3:e003389. doi: 10.1136/bmjopen-2013-003389 PMID: 24038008

14. Lewis JD, Bilker WB, Weinstein RB, Strom BL. The relationship between time since registration and measured incidence rates in the General Practice Research Database. Pharmacoepidemiol Drug Saf. 2005; 14:443-451. doi: 10.1002/pds.1115 PMID: 15898131

15. Austin PC. Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples. Stat Med. 2009; 28:3083-3107. doi: 10.1002/sim.3697 PMID: 19757444 [OpenAIRE]

46 references, page 1 of 4
Abstract
Background Bariatric surgery is becoming a more widespread treatment for obesity. Comprehensive evidence of the long-term effects of contemporary surgery on a broad range of clinical outcomes in large populations treated in routine clinical practice is lacking. The objective of this study was to measure the association between bariatric surgery, weight, body mass index, and obesity-related co-morbidities. Methods and Findings This was an observational retrospective cohort study using data from the United Kingdom Clinical Practice Research Datalink. All 3,882 patients registered in the database and with bariatric surgery on or before 31 December 2014 were include...
Subjects
free text keywords: Research Article, Medicine, R, General Medicine, Weight loss, medicine.symptom, Surgery, medicine.medical_specialty, Retrospective cohort study, Sleeve gastrectomy, medicine.medical_treatment, Obesity, medicine.disease, Population, education.field_of_study, education, Type 2 diabetes, business.industry, business, Body mass index, Cohort study
46 references, page 1 of 4

1. Department of Health. Obesity general information. 1 February 2011. Available: http://webarchive. nationalarchives.gov.uk/+/www.dh.gov.uk/en/Publichealth/Obesity/DH_078098. Accessed 8 May 2015.

2. World Health Organization. Obesity and overweight. Fact sheet no. 311. January 2015. Available: http://www.who.int/mediacentre/factsheets/fs311/en/index.html. Accessed 8 May 2015.

3. National Institute for Health and Care Excellence. Obesity prevention. NICE guidelines CG43. December 2006. Available: http://guidance.nice.org.uk/CG43. Accessed 8 May 2015.

4. National Health Service Commissioning Board. Clinical commissioning policy: complex and specialised obesity surgery. April 2013. NHSCB/A05/P/a. Available: https://www.england.nhs.uk/wp-content/ uploads/2013/04/a05-p-a.pdf. Accessed 20 November 2015.

5. National Heart, Lung, and Blood Institute Obesity Education Initiative Expert Panel on the Identification, Evaluation, and Treatment of Obesity in Adults. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report. Report No. 98-4083. Bethesda (Maryland): National Heart, Lung, and Blood Institute; 1998.

6. National Institute for Health and Care Excellence. Obesity: identification, assessment and management. NICE guidelines CG189. November 2014. Available: http://www.nice.org.uk/guidance/cg189. Accessed 15 May 2015.

7. Courcoulas AP, Goodpaster BH, Eagleton JK, Belle SH, Kalarchian MA, Lang W, et al. Surgical vs medical treatments for type 2 diabetes mellitus: a randomized clinical trial. JAMA Surg. 2014; 149:707- 715. doi: 10.1001/jamasurg.2014.467 PMID: 24899268 [OpenAIRE]

8. O'Brien PE, Brennan L, Laurie C, Brown W. Intensive medical weight loss or laparoscopic adjustable gastric banding in the treatment of mild to moderate obesity: long-term follow-up of a prospective randomised trial. Obes Surg. 2013 23:1345-1353. doi: 10.1007/s11695-013-0990-3 PMID: 23760764

9. Schauer PR, Kashyap SR, Wolski K, Brethauer SA, Kirwan JP, Pothier CE, et al. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med. 2012; 366:1567-1576. doi: 10.1056/NEJMoa1200225 PMID: 22449319

10. Mingrone G, Panunzi S, De Gaetano A, Guidone C, Iaconelli A, Leccesi L, et al. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med. 2012; 366:1577-1585. doi: 10. 1056/NEJMoa1200111 PMID: 22449317

11. Campbell J, Dedman DJ, Eaton SC, Gallagher AM, Williams TJ. Is the CPRD GOLD population comparable to the U.K. population? Pharmacoepidemiol Drug Saf 2013; 22(Suppl 1):280.

12. Herrett E, Thomas SL, Schoonen WM, Smeeth L, Hall AJ. Validation and validity of diagnoses in the General Practice Research Database: a systematic review. Br J Clin Pharmacol. 2010; 69:4-14. doi: 10.1111/j.1365-2125.2009.03537.x PMID: 20078607 [OpenAIRE]

13. Bhaskaran K, Forbes H, Douglas I, Leon D, Smeeth L. Representativeness and optimal use of body mass index (BMI) in the UK Clinical Practice Research Datalink (CPRD). BMJ Open 2013; 3:e003389. doi: 10.1136/bmjopen-2013-003389 PMID: 24038008

14. Lewis JD, Bilker WB, Weinstein RB, Strom BL. The relationship between time since registration and measured incidence rates in the General Practice Research Database. Pharmacoepidemiol Drug Saf. 2005; 14:443-451. doi: 10.1002/pds.1115 PMID: 15898131

15. Austin PC. Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples. Stat Med. 2009; 28:3083-3107. doi: 10.1002/sim.3697 PMID: 19757444 [OpenAIRE]

46 references, page 1 of 4
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