publication . Article . 2004

Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: A Case–Control Study in Newborn Boys

Frank H. Pierik; Alex Burdorf; James A. Deddens; Rikard E. Juttmann; Rob F.A. Weber;
Open Access English
  • Published: 01 Sep 2004 Journal: Environmental Health Perspectives, volume 112, issue 15, pages 1,570-1,576 (issn: 0091-6765, eissn: 1552-9924, Copyright policy)
  • Publisher: National Institue of Environmental Health Sciences
Little is known on environmental risk factors for cryptorchidism and hypospadias, which are among the most frequent congenital abnormalities. The aim of our study was to identify risk factors for cryptorchidism and hypospadias, with a focus on potential endocrine disruptors in parental diet and occupation. In a case–control study nested within a cohort of 8,698 male births, we compared 78 cryptorchidism cases and 56 hypospadias cases with 313 controls. The participation rate was 85% for cases and 68% for controls. Through interviews, information was collected on pregnancy aspects and personal characteristics, lifestyle, occupation, and dietary phytoestrogen inta...
free text keywords: Children's Health, Articles, children, cryptorchidism, endocrine disruptor, environment, epidemiology, hypospadias, nutrition, occupational exposure, testis, Odds ratio, Case-control study, Pediatrics, medicine.medical_specialty, medicine, Risk factor, Paternal Exposure, medicine.disease, Premature birth, business.industry, business, Small for gestational age, Pregnancy
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publication . Article . 2004

Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: A Case–Control Study in Newborn Boys

Frank H. Pierik; Alex Burdorf; James A. Deddens; Rikard E. Juttmann; Rob F.A. Weber;