publication . Other literature type . Article . 2007

Prophylactic vaccination against human papillomavirus infection and disease in women : a systematic review of randomized controlled trials

L. Rambout; L. Hopkins; B. Hutton; D. Fergusson;
Open Access English
  • Published: 28 Aug 2007
  • Publisher: Canadian Medical Association
Abstract
Background: Human papillomavirus (HPV) is now known to be a necessary cause of cervical cancer, and prophylactic HPV vaccines aimed at preventing genital warts, precancerous cervical lesions and cervical cancer are now available. To gauge the potential impact on disease burden, we performed a systematic review of the evidence from randomized controlled trials. Methods: We conducted a systematic search of the literature to identify all randomized controlled trials of prophylactic HPV vaccination. Reports in 5 electronic databases covering 1950 to June 2007 (MEDLINE, MEDLINE in process, EMBASE, the Cochrane Central Registry of Controlled Trials and the Cochrane Li...
Subjects
free text keywords: Research, General Medicine, Pathology, medicine.medical_specialty, medicine, business.industry, business, Cervical intraepithelial neoplasia, medicine.disease, Genital warts, Squamous intraepithelial lesion, Cochrane Library, HPV infection, Papillomaviridae, biology.organism_classification, biology, HPV vaccines, Cervical cancer
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publication . Other literature type . Article . 2007

Prophylactic vaccination against human papillomavirus infection and disease in women : a systematic review of randomized controlled trials

L. Rambout; L. Hopkins; B. Hutton; D. Fergusson;