publication . Article . Other literature type . 1999

Shunting Effects in Patients with Idiopathic Normal Pressure Hydrocephalus; Correlation with Cerebral and Leptomeningeal Biopsy Findings

Bech, R. A.; Waldemar, G.; Gjerris, F.; Klinken, L.; Juhler, M.;
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  • Published: 15 Jun 1999 Journal: Acta Neurochirurgica, volume 141, pages 633-639 (issn: 0001-6268, eissn: 0942-0940, Copyright policy)
  • Publisher: Springer Science and Business Media LLC
Abstract
Normal Pressure Hydrocephalus (NPH) is a potentially treatable syndrome with abnormal cerebrospinal fluid dynamics. Meningeal fibrosis and/or obliteration of the subarachnoid space have been suggested as one of the patho-anatomical substrates. However, other types of adult onset dementia, predominantly Alzheimer's disease and Vascular Dementia, may mimic the clinical NPH characteristics.  The purpose of the present study was to correlate cerebral parenchymal and leptomeningeal biopsy findings to the clinical outcome after CSF shunting in a prospective group of idiopathic NPH (INPH) patients. The study comprises 27 patients with INPH, diagnosed and shunted accord...
Subjects
free text keywords: Surgery, Clinical Neurology
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