publication . Other literature type . Article . 1918

TWO NEW FACTORS IN BLOOD COAGULATION—HEPARIN AND PRO-ANTITHROMBIN

W. H. Howell; Emmett Holt;
  • Published: 01 Dec 1918
  • Publisher: American Physiological Society
Abstract
A survey of the results of recent work indicates that at least six different substances are concerned in one way or another in the process of blood coagulation; namely, fibrinogen, thrombin, prothrombin, calcium, antithrombin and the so-called zymoplastic or thromboplastic substances furnished bv the body cells in general, including the blood corpuscles. With regard to the last mentioned factor satisfactory evidence has been obtained to show that the active material in tissue extracts is a phosphatid (1) (cephalin). Work that has been going on in t-his laboratory during the past two or three years shows that we must! add two other substances to this list of fibr...
Subjects
Medical Subject Headings: circulatory and respiratory physiology
free text keywords: Physiology (medical), Heparin, medicine.drug, medicine, Internal medicine, medicine.medical_specialty, Blood serum, Blood plasma, Fibrin, biology.protein, biology, Thrombin, Fibrinogen, Chemistry, Calcium, chemistry.chemical_element, Endocrinology, Antithrombin
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publication . Other literature type . Article . 1918

TWO NEW FACTORS IN BLOOD COAGULATION—HEPARIN AND PRO-ANTITHROMBIN

W. H. Howell; Emmett Holt;