publication . Other literature type . Article . 2007

A second-generation combined linkage–physical map of the human genome

Matise, T. C.; Chen, F.; Chen, W.; De La Vega, F. M.; Hansen, M.; He, C.; Hyland, F. C.L.; Kennedy, G. C.; Kong, X.; Murray, S. S.; ...
Open Access English
  • Published: 01 Dec 2007
  • Publisher: Cold Spring Harbor Laboratory Press
Abstract
We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map inform...
Subjects
free text keywords: Resource, Gene map, Genetic marker, Physical Chromosome Mapping, Human genome, Bioinformatics, Genetic linkage, Genetics, Interpolation, Biology, Genome human
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