publication . Article . Other literature type . 2004

Fibrillary Glomerulonephritis and Immunotactoid Glomerulopathy

Béla Iványi; Péter Degrell;
Open Access
  • Published: 06 Aug 2004 Journal: Journal of the American Society of Nephrology, volume 19, pages 34-37 (issn: 1046-6673, eissn: 1533-3450, Copyright policy)
  • Publisher: American Society of Nephrology (ASN)
Summary The features of GPs with Congo red-negative, non-cryoglobulinaemic deposits have been surveyed. Thesedisorders are rare and clinically heterogeneous andtheir pathogenesis is unclear. There is controversyconcerning the nomenclature of Congo-red negativeglomerular fibrilloses. A practical and reproducibleapproach is to classify these GPs on the basis of thesubstructure and arrangement of the deposits assessedat conventional electron microscopic magnifications.Accordingly, FGN and ITG can be identified. FGN ischaracterized by randomly arranged microfibrils (dia-meter: 12–30nm) composed of subclass-restrictedpolyclonal IgG and a low incidence of underlyingsystem...
free text keywords: Nephrology, General Medicine, Transplantation, Medicine, business.industry, business, Kidney disease, medicine.disease, Glomerulopathy, Glomerular deposits, Amyloid, Glomerulonephritis, Fibrillary Glomerulonephritis, Amyloid fibril, Pathology, medicine.medical_specialty, Biopsy, medicine.diagnostic_test, Pathogenesis, Cryoglobulins, Gammopathy, Electron microscopic, Renal biopsy
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