publication . Other literature type . Article . 1996

A longitudinal MRI study

Nick Fox; Warrington, Ek; Freeborough, Pa; Hartikainen, P.; Kennedy, Am; Stevens, Jm; Rossor, Mn;
  • Published: 01 Jan 1996
  • Publisher: Oxford University Press (OUP)
Abstract
The hippocampal formation (HF) is known from pathological and MRI studies to be severely atrophied in established Alzheimer's disease. However, it is unclear when the earliest changes in the HF occur We performed a longitudinal study of asymptomatic individuals at risk of autosomal dominant familial Alzheimer's disease in order to assess presymptomatic changes in the HF. Seven at risk members of a familial Alzheimer's disease pedigree associated with the amyloid precursor protein 717 valine to glycine mutation underwent serial MR scanning and neuropsychological assessments over 3 years. These assessments were compared with results from 38 normal controls. During...
Subjects
free text keywords: Pathology, medicine.medical_specialty, medicine, Atrophy, medicine.disease, Neuroscience, Asymptomatic, medicine.symptom, Alzheimer's disease, Degenerative disease, Central nervous system disease, Dementia, business.industry, business, Longitudinal study, Cerebral atrophy
Download fromView all 3 versions
Brain
Article
Provider: UnpayWall
Brain
Article
Provider: Crossref
http://dx.doi.org/10.1093/brai...
Other literature type . 1996
Provider: Datacite
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue
publication . Other literature type . Article . 1996

A longitudinal MRI study

Nick Fox; Warrington, Ek; Freeborough, Pa; Hartikainen, P.; Kennedy, Am; Stevens, Jm; Rossor, Mn;