publication . Article . Other literature type . 2001

An Analysis of the Cytokine Database from the Vesnarinone Trial (VEST)

Deswal, Anita; Petersen, Nancy J.; Feldman, Arthur M.; Young, James B.; White, Bill G.; Mann, Douglas L.;
Open Access
  • Published: 24 Apr 2001 Journal: Circulation, volume 103, pages 2,055-2,059 (issn: 0009-7322, eissn: 1524-4539, Copyright policy)
  • Publisher: Ovid Technologies (Wolters Kluwer Health)
Background—Previous reports have shown that elevated circulating levels of cytokines and/or cytokine receptors predict adverse outcomes in patients with heart failure. However, these studies were limited by small numbers of patients and/or they were performed in a single center. In addition, these studies did not have sufficient size to address the influence of age, race, sex, and cause of heart failure on the circulating levels of these inflammatory mediators in patients with heart failure. Methods and Results—We analyzed circulating levels of cytokines (tumor necrosis factor [TNF] and interleukin-6) and their cognate receptors in 1200 consecutive patients who ...
free text keywords: Physiology (medical), Cardiology and Cardiovascular Medicine
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Other literature type . 2001
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Article . 2001
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