publication . Article . Other literature type . 1984

Familial Premature Ovarian Failure

Donald Mattison; Evans, M. I.; Schwimmer, W. B.; White, B. J.; Jensen, B.; Schulman, J. D.;
Open Access
  • Published: 01 Nov 1984
Abstract
Premature menopause, ovarian failure younger than 40 years of age, is relatively rare but may preclude childbearing for some women who delay attempts at fertility. We present five kindreds in which a genetic association for premature ovarian failure is strongly suggested. Transmission is either autosomal or (less likely) X-linked dominant in these examples. Chromosomal abnormalities, history of diseases, and toxic chemical or viral exposures previously associated with premature ovarian failure could not be demonstrated in these women. This suggests that these kindreds all represent familial idiopathic premature ovarian failure. These data support the need for me...
Subjects
Medical Subject Headings: endocrine system diseases
free text keywords: Obstetrics and Gynaecology, General Medicine, Research Article
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