publication . Article . 2012

Potential impact of a nine-valent vaccine in human papillomavirus related cervical disease

Open Access English
  • Published: 01 Dec 2012 Journal: Infectious Agents and Cancer (issn: 1750-9378, Copyright policy)
  • Publisher: BMC
  • Country: Spain
<p>Abstract</p> <p>Background</p> <p>Information on human papillomavirus (HPV) type distribution is necessary to evaluate the potential impact of current and future HPV vaccines. We estimated the relative contribution (RC) to invasive cervical cancer (ICC) and precancerous cervical lesions of the nine HPV types (HPV 6/11/16/18/31/33/45/52/58) included in an HPV vaccine currently under development.</p> <p>Methods</p> <p>Estimations on ICC were based on an international study of 8,977 HPV positive cases and estimations on precancerous cervical lesions were extracted from a published meta-analysis including 115,789 HPV positive women. Globocan 2008 and 2010 World P...
Medical Subject Headings: female genital diseases and pregnancy complications
free text keywords: Papil·lomavirus, Càncer de coll uterí, Papillomaviruses, Cervix cancer, Human papillomavirus, Cervical cancer, Genotype, Epidemiology, Human papillomavirus vaccines, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Infectious and parasitic diseases, RC109-216, Research Article, Cancer Research, Oncology, Infectious Diseases
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