research data . Image . 2011

Genetic Analysis Workshop 15: simulation of a complex genetic model for rheumatoid arthritis in nuclear families including a dense SNP map with linkage disequilibrium between marker loci and trait loci-0

Miller, Michael B; Lind, Gregg R; Li, Na; Jang, Soon-Young;
  • Published: 01 Jan 2011
  • Publisher: Figshare
Abstract
And observed variables are represented as rectangles. The RA hazard is a continuous variable that is dichotomized into affected/unaffected before it is observed, and severity is polytomized into five levels before it is observed. Arrows indicate where effects of variables are manifested. For example, HLA-DRB1 affects both anti-CCP levels and RA hazard, but the strength of its effect on anti-CCP is controlled by Locus E genotype and the effect of HLA-DRB1 on RA hazard is controlled by Locus A genotype. The incorrect cM locations for Loci D and H are given, see the note on Table 1.<b>Copyright information:</b>Taken from "Genetic Analysis Workshop 15: simulation of...
Subjects
free text keywords: Genetics
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Image . 2011
Provider: Datacite
figshare
Image . 2011
Provider: Datacite
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