publication . Article . Other literature type . 2009

Functional analysis of insertion sequence ISAba1, responsible for genomic plasticity of Acinetobacter baumannii.

Mugnier, Pauline D.; Poirel, Laurent; Nordmann, Patrice;
Open Access
  • Published: 09 Jan 2009 Journal: Journal of Bacteriology, volume 191, pages 2,414-2,418 (issn: 0021-9193, eissn: 1098-5530, Copyright policy)
  • Publisher: American Society for Microbiology
Abstract
<jats:title>ABSTRACT</jats:title> <jats:p>IS<jats:italic>Aba1</jats:italic> is an insertion sequence that is widely distributed in <jats:italic>Acinetobacter baumannii</jats:italic>. We demonstrated here that IS<jats:italic>Aba1</jats:italic> and the composite transposon Tn<jats:italic>2006</jats:italic> are capable of transposition, generating 9-bp target site duplications. The expression of the IS<jats:italic>Aba1</jats:italic> transposase-encoding gene was downregulated by translational frameshifting.</jats:p>
Subjects
free text keywords: Molecular Biology, Microbiology, Translational frameshift, Insertion sequence, Transposase, Sequence alignment, Genetics, Transposition (music), Biology, Acinetobacter baumannii, biology.organism_classification, Transposable element, Composite transposon, Bacteriophages, Transposons, and Plasmids
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publication . Article . Other literature type . 2009

Functional analysis of insertion sequence ISAba1, responsible for genomic plasticity of Acinetobacter baumannii.

Mugnier, Pauline D.; Poirel, Laurent; Nordmann, Patrice;