publication . Other literature type . Article . 1998

Human papillomaviruses are commonly found in normal skin of immunocompetent hosts.

Astori, Giuseppe; Lavergne, Donna; Benton, Claire; Höckmayr, Birgit; Egawa, Kiyofumi; Garbe, Claus; de Villiers, Ethel-Michele;
  • Published: 01 May 1998
  • Publisher: Elsevier BV
Abstract
We have previously demonstrated, by the combined application of two degenerate polymerase chain reaction primer sets, the presence of human papillomavirus (HPV) DNA in 91% of cutaneous squamous cell cancers from renal allograft recipients, with multiple types being present in one-third of these tumors. Five HPV types – HPV 20, HPV 23, HPV 38, DL40, and DL267 – accounted for 73% of positive results. These HPV types are all related to the epidermodysplasia verruciformis group, and HPV 38 was originally isolated from a melanoma. The aims of this study were to determine: (i) whether HPV DNA could readily be demonstrated in skin tumors, as well as in perilesional ski...
Subjects
Medical Subject Headings: virus diseasesfemale genital diseases and pregnancy complications
free text keywords: Cell Biology, Biochemistry, Molecular Biology, Dermatology, Immunology, Epidermodysplasia verruciformis, medicine.disease, medicine, Pathology, medicine.medical_specialty, Betapapillomavirus, Biology, Virus, Melanoma, Papillomaviridae, biology.organism_classification, Skin cancer, Primer (molecular biology), Polymerase chain reaction, law.invention, law
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