publication . Article . Other literature type . 2014

Temporal and spatial characteristics of high frequency oscillations as a new biomarker in epilepsy

Dümpelmann, Matthias; Jacobs, Julia; Schulze-Bonhage, Andreas;
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  • Published: 30 Dec 2014 Journal: Epilepsia, volume 56, pages 197-206 (issn: 0013-9580, Copyright policy)
  • Publisher: Wiley
Abstract
Summary Objective Interictal high frequency oscillations (HFOs) are a promising candidate as a biomarker in epilepsy as well as for defining the seizure-onset zone as for the prediction of the surgical outcome after epilepsy surgery. The purpose of the study is to investigate properties of HFOs in long-term recordings with respect to the sleep–wake cycle and anatomic regions to verify previous results based on observations from short intervals and patients mainly with temporal lobe epilepsy to the analysis of hours of recordings and focal epilepsies with extratemporal origin. Methods Automatic HFO detection using a radial basis function neural network detector w...
Subjects
free text keywords: Neurology, Clinical Neurology
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