publication . Other literature type . Article . 1999

Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli

J. D. Jentsch; J. R. Taylor;
  • Published: 21 Oct 1999
  • Publisher: Springer Science and Business Media LLC
Abstract
Drug abuse and dependence define behavioral states involving increased allocation of behavior towards drug seeking and taking at the expense of more appropriate behavioral patterns. As such, addiction can be viewed as increased control of behavior by the desired drug (due to its unconditioned, rewarding properties). It is also clear that drug-associated (conditioned) stimuli acquire heightened abilities to control behaviors. These phenomena have been linked with dopamine function within the ventral striatum and amygdala and have been described specifically in terms of motivational and incentive learning processes. New data are emerging that suggest that regions ...
Subjects
free text keywords: Ventral striatum, medicine.anatomical_structure, medicine, Substance abuse, medicine.disease, Addiction, media_common.quotation_subject, media_common, Nucleus accumbens, Neuroscience, Amphetamine, medicine.drug, Psychology, Amygdala, Mesolimbic pathway, Impulsivity, medicine.symptom
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publication . Other literature type . Article . 1999

Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli

J. D. Jentsch; J. R. Taylor;