publication . Article . Other literature type . 2007

Prepubertal orchiopexy for cryptorchidism may be associated with lower risk of testicular cancer.

Walsh, Thomas J.; Dall’Era, Marc A.; Croughan, Mary S.; Carroll, Peter R.; Turek, Paul J.;
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  • Published: 01 Oct 2007 Journal: Journal of Urology, volume 178, pages 1,440-1,446 (issn: 0022-5347, eissn: 1527-3792, Copyright policy)
  • Publisher: Ovid Technologies (Wolters Kluwer Health)
Abstract
Purpose: Current indications for orchiopexy are to decrease the risk of infertility and to facilitate testicular self-examination. Although the increased risk of germ cell cancer in cryptorchid testes is undisputed, it is unclear whether orchiopexy affects the natural history of testis cancer development. We hypothesize that early orchiopexy is protective against subsequent development of testicular germ cell cancer.Materials and Methods: We conducted a systematic review and meta-analysis of the literature. Studies pertaining to cryptorchidism and testicular cancer risk were retrieved by searching MEDLINE, BIOSIS and the Cochrane Library, using cryptorchidism as...
Subjects
Medical Subject Headings: endocrine system
free text keywords: Urology
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