publication . Article . Other literature type . 2001

RANTES: a versatile and controversial chemokine

Appay, Victor; Rowland-Jones, Sarah L;
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  • Published: 01 Feb 2001 Journal: Trends in Immunology, volume 22, pages 83-87 (issn: 1471-4906, Copyright policy)
  • Publisher: Elsevier BV
  • Country: United Kingdom
Abstract
Abstract The activity of the chemokine RANTES is not restricted merely to chemotaxis. It is a powerful leukocyte activator, a feature potentially relevant in a range of inflammatory disorders. RANTES has attracted attention because it can potently suppress and, in some circumstances, enhance HIV replication. These characteristics are critically dependent on its ability to self-aggregate and bind to glycosaminoglycans.
Subjects
Medical Subject Headings: food and beverages
free text keywords: Immunology, Immunology and Allergy
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