publication . Other literature type . Article . 1995

A Reference Region for Functional Brain Image (PET) Analysis

Satoshi Minoshima; Kirk A. Frey; Norman L. Foster; David E. Kuhl;
  • Published: 01 Jul 1995
  • Publisher: Ovid Technologies (Wolters Kluwer Health)
Abstract
Our goal was to examine regional preservation of energy metabolism in Alzheimer disease (AD) and to evaluate effects of PET data normalization to reference regions. Regional metabolic rates in the pons, thalamus, putamen, sensorimotor cortex, visual cortex, and cerebellum (reference regions) were determined stereotaxically and examined in 37 patients with probable AD and 22 normal controls based on quantitative {sup 18}FDG-PET measurements. Following normalization of metabolic rates of the parietotemporal association cortex and whole brain to each reference region, distinctions of the two groups were assessed. The pons showed the best preservation of glucose met...
Subjects
free text keywords: Radiology Nuclear Medicine and imaging, Alzheimer's disease, medicine.disease, medicine, Pons, Thalamus, Degenerative disease, Pathology, medicine.medical_specialty, Cortex (botany), Visual cortex, medicine.anatomical_structure, Putamen, business.industry, business, Cerebellum
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publication . Other literature type . Article . 1995

A Reference Region for Functional Brain Image (PET) Analysis

Satoshi Minoshima; Kirk A. Frey; Norman L. Foster; David E. Kuhl;