publication . Other literature type . Article . 2009

Aconitum in traditional Chinese medicine: a valuable drug or an unpredictable risk?

Judith Singhuber; Ming Zhu; Sonja Prinz; Brigitte Kopp;
  • Published: 01 Oct 2009
  • Publisher: Elsevier BV
Abstract Aconitum species have been used in China as an essential drug in Traditional Chinese Medicine (TCM) for 2000 years. Reviewing the clinical application of Aconitum, their pharmacological effects, toxicity and detoxifying measures, herb–herb interactions, clinical taboos, famous herbal formulas, traditional and current herbal processing methods based upon a wide range of literature investigations serve as a case study to explore the multidisciplinary implications of botanicals used in TCM. The toxicological risk of improper usage of Aconitum remains very high, especially in countries like China, India and Japan. The toxicity of Aconitum mainly derives fro...
free text keywords: Pharmacology, Drug Discovery
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