publication . Article . Other literature type . 2018

Reliability of fMRI for Studies of Language in Post-Stroke Aphasia Subjects

Eaton, Kenneth P.; Szaflarski, Jerzy P.; Altaye, Mekibib; Ball, Angel L.; Kissela, Brett M.; Banks, Christi; Holland, Scott K.;
Open Access
  • Published: 13 Nov 2018 Journal: NeuroImage, volume 41, pages 311-322 (issn: 1053-8119, Copyright policy)
  • Publisher: Elsevier BV
Abstract
Quantifying change in brain activation patterns associated with post-stroke recovery and reorganization of language function over time requires accurate understanding of inter-scan and inter-subject variability. Here we report inter-scan variability measures for fMRI activation patterns associated with verb generation (VG) and semantic decision/tone decision (SDTD) tasks in 4 healthy controls and 4 aphasic left middle cerebral artery (LMCA) stroke subjects. A series of 10 fMRI scans was completed on a 4T Varian scanner for each task for each subject, except for one stroke subject who completed 5 and 6 scans for SDTD and VG, thus yielding 35 and 36 total stroke s...
Subjects
free text keywords: Cognitive Neuroscience, Neurology, Intraclass correlation, Left middle cerebral artery, Magnetic resonance imaging, medicine.diagnostic_test, medicine, Developmental psychology, Aphasia, medicine.symptom, Brain mapping, Stroke, medicine.disease, Brain activation, Language function, Psychology, Article
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