publication . Article . 2003

Linking exposure to environmental pollutants with biological effects.

Ole Hertel; Steffen Loft; Peter Møller; Steen Solvang Jensen; Mette Sørensen; Herman Autrup; Peter Vinzents; Lisbeth E. Knudsen;
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  • Published: 01 Jan 2003
Abstract
Abstract Exposure to ambient air pollution has been associated with cancer. Ambient air contains a complex mixture of toxics, including particulate matter (PM) and benzene. Carcinogenic effects of PM may relate both to the content of PAH and to oxidative DNA damage generated by transition metals, benzene, metabolism and inflammation. By means of personal monitoring and biomarkers of internal dose, biologically effective dose and susceptibility, it should be possible to characterize individual exposure and identify air pollution sources with relevant biological effects. In a series of studies, individual exposure to PM2.5, nitrogen dioxide (NO2) and benzene has b...
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doi: 10.1016/j.mrrev.2003.06.010
Subjects
free text keywords: Genetics, Health, Toxicology and Mutagenesis, ERCC1, Benzene, chemistry.chemical_compound, chemistry, Toxicology, Carcinogen, Oxidative stress, medicine.disease_cause, medicine, DNA damage, Metabolism, Biochemistry, DNA repair, Pollutant
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Article . 2003
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