publication . Other literature type . Article . 2015

Bariatric–metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial

Geltrude Mingrone; Simona Panunzi; Andrea De Gaetano; Caterina Guidone; Amerigo Iaconelli; Giuseppe Nanni; Marco Castagneto; Stefan Bornstein; Francesco Rubino;
  • Published: 01 Sep 2015
  • Publisher: Elsevier BV
Summary Background Randomised controlled trials have shown that bariatric surgery is more effective than conventional treatment for the short-term control of type-2 diabetes. However, published studies are characterised by a relatively short follow-up. We aimed to assess 5 year outcomes from our randomised trial designed to compare surgery with conventional medical treatment for the treatment of type 2 diabetes in obese patients. Methods We did our open-label, randomised controlled trial at one diabetes centre in Italy. Patients aged 30–60 years with a body-mass index of 35 kg/m 2 or more and a history of type 2 diabetes lasting at least 5 years were randomly as...
free text keywords: Type 2 diabetes, medicine.disease, medicine, Surgery, medicine.medical_specialty, Randomized controlled trial, law.invention, law, Diabetes mellitus, Intention-to-treat analysis, Complication, business.industry, business, Clinical endpoint, Biliopancreatic Diversion, Myocardial infarction
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