publication . Other literature type . Article . 2002

Neural Systems and Cue-Induced Cocaine Craving

K Bonson;
  • Published: 01 Mar 2002
  • Publisher: Springer Science and Business Media LLC
Abstract
We have extended our previous work investigating the neural correlates of cue-induced cocaine craving through the use of positron emission tomography with greater spatial resolution (<4.6 mm), an evocative script, and a pixel-by-pixel analysis. Craving and cerebral glucose metabolism were measured after presentation of cocaine-related or neutral cues to 11 cocaine abusers. Cocaine cues elicited a higher degree of craving than has been previously reported and resulted in left hemispheric activation of lateral amygdala, lateral orbitofrontal cortex, and rhinal cortex and right hemispheric activation of dorsolateral prefrontal cortex and cerebellum. The intensity o...
Subjects
Medical Subject Headings: mental disordersbehavioral disciplines and activities
free text keywords: Pharmacology, Psychiatry and Mental health, Anesthesia, Neural correlates of consciousness, Stimulus (physiology), Psychology, Neuroscience, Amygdala, medicine.anatomical_structure, medicine, Neuroimaging, Prefrontal cortex, Dorsolateral prefrontal cortex, Craving, medicine.symptom, Rhinal cortex
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