publication . Article . Other literature type . 2002

Escherichia coli harboring Shiga toxin 2 gene variants: frequency and association with clinical symptoms

Friedrich, Alexander W.; Bielaszewska, Martina; Zhang, Wen‐Lan; Pulz, Matthias; Kuczius, Thorsten; Ammon, Andrea; Karch, Helge;
Open Access
  • Published: 01 Jan 2002 Journal: The Journal of Infectious Diseases, volume 185, pages 74-84 (issn: 0022-1899, eissn: 1537-6613, Copyright policy)
  • Publisher: Oxford University Press (OUP)
Abstract
Shiga toxin (Stx)-producing Escherichia coli (STEC) from patients with hemolytic-uremic syndrome (HUS), patients with diarrhea without HUS, or asymptomatic subjects were genotyped to assess associations between stx2 variants and clinical manifestations of infection. Neither stx2d nor stx2e was found in 268 STEC isolates from patients with HUS. Of 262 STEC isolates from patients with diarrhea, stx(2d) was found in 41 (15.6%; P<.000001), and stx2e was found in 12 (4.6%; P=.0004). The stx2c genotype frequency was similar among isolates from patients with HUS (3.7%) and diarrhea (5.0%). The frequencies of stx2c, stx2d, and stx2e among 96 STEC isolates from asymptoma...
Subjects
Medical Subject Headings: hemic and lymphatic diseasesfluids and secretionsbacteriabacterial infections and mycosesanimal diseases
free text keywords: Microbiology, Genotype, Virology, Asymptomatic, medicine.symptom, medicine, Shiga toxin, biology.protein, biology, Shiga-like toxin, chemistry.chemical_compound, chemistry, Typing, Serotype, STX2, Diarrhea, Immunology, business.industry, business
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publication . Article . Other literature type . 2002

Escherichia coli harboring Shiga toxin 2 gene variants: frequency and association with clinical symptoms

Friedrich, Alexander W.; Bielaszewska, Martina; Zhang, Wen‐Lan; Pulz, Matthias; Kuczius, Thorsten; Ammon, Andrea; Karch, Helge;