publication . Article . Other literature type . 2011

Automatic classification of patients with Alzheimer's disease from structural MRI: A comparison of ten methods using the ADNI database

Jérôme Tessieras;
Open Access English
  • Published: 15 May 2011
  • Publisher: HAL CCSD
  • Country: France
Abstract
International audience; Recently, several high dimensional classification methods have been proposed to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls (CN) based on T1-weighted MRI. However, these methods were assessed on different populations, making it difficult to compare their performance. In this paper, we evaluated the performance of ten approaches (five voxel-based methods, three methods based on cortical thickness and two methods based on the hippocampus) using 509 subjects from the ADNI database. Three classification experiments were performed: CN vs AD, CN vs MCIc (MCI w...
Subjects
free text keywords: Magnetic resonance imaging, MCI, Alzheimer's disease, AD, Support vector machines, converter, prodromal, classification, magnetic, [INFO.INFO-IM]Computer Science [cs]/Medical Imaging, Cognitive Neuroscience, Neurology, Psychology, Feature selection, Support vector machine, Cognitive impairment, Voxel, computer.software_genre, computer, Database
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