publication . Other literature type . Article . 2011

Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88

Andersen, M. R.; Salazar, M. P.; Schaap, P. J.; van de Vondervoort, P. J. I.; Culley, D.; Thykaer, J.; Frisvad, J. C.; Nielsen, K. F.; Albang, R.; Albermann, K.; ...
Open Access English
  • Published: 04 May 2011
  • Publisher: Cold Spring Harbor Laboratory Press
Abstract
The filamentous fungus Aspergillus niger exhibits great diversity in its phenotype. It is found globally, both as marine and terrestrial strains, produces both organic acids and hydrolytic enzymes in high amounts, and some isolates exhibit pathogenicity. Although the genome of an industrial enzyme-producing A. niger strain (CBS 513.88) has already been sequenced, the versatility and diversity of this species compel additional exploration. We therefore undertook whole- genome sequencing of the acidogenic A. niger wild-type strain (ATCC 1015) and produced a genome sequence of very high quality. Only 15 gaps are present in the sequence, and half the telomeric regio...
Subjects
free text keywords: Citric acid, Glucan 1, 4 alpha glucosidase, Transfer RNA, Research, fungal metabolite, linkage group, saccharomyces-cerevisiae, liquid-chromatography, gene ontology, mycotoxins, expression, identification, recognition, karyotype, Whole genome sequencing, Comparative genomics, Gene, Genomics, Aspergillus niger, biology.organism_classification, biology, Gene rearrangement, Genetic variation, Bioinformatics, Genetics, Genome
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