publication . Article . Other literature type . 2009

Genes, gene clusters, and biosynthesis of trichothecenes and fumonisins in Fusarium

Alexander, Nancy J.; Proctor, Robert H.; McCormick, Susan P.;
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  • Published: 28 Jul 2009 Journal: Toxin Reviews, volume 28, pages 198-215 (issn: 1556-9543, eissn: 1556-9551, Copyright policy)
  • Publisher: Informa UK Limited
Abstract
Trichothecenes and fumonisins are mycotoxins produced by Fusarium, a filamentous fungus that can cause disease in barley, maize, rice, wheat, and some other crop plants. Research on the genetics and biochemistry of trichothecene and fumonisin biosynthesis has provided important insights into the genetic and biochemical pathways in Fusarium that lead to formation of these mycotoxins. In Fusarium, trichothecene biosynthetic enzymes are encoded by genes at three loci: the single-gene TRI101 locus, the two-gene TRI1-TRI16 locus, and the 12-gene core TRI cluster. In contrast, fumonisin biosynthetic enzymes identified to date are all located at one locus, the 17-gene ...
Subjects
Medical Subject Headings: food and beverages
free text keywords: Toxicology, Fusarium, biology.organism_classification, biology, Metabolic pathway, Fusarium sporotrichioides, Fumonisin, chemistry.chemical_compound, chemistry, Trichothecene, Gene, Mycotoxin, Locus (genetics), Biochemistry
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