publication . Article . Other literature type . 2011

The syndrome of cognitive impairment in amyotrophic lateral sclerosis: a population-based study

Phukan, J.; Elamin, M.; Bede, P.; Jordan, N.; Gallagher, L.; Byrne, S.; Lynch, C.; Pender, N.; Hardiman, O.;
  • Published: 11 Aug 2011 Journal: Journal of Neurology, Neurosurgery & Psychiatry, volume 83, pages 102-108 (issn: 0022-3050, eissn: 1468-330X, Copyright policy)
  • Publisher: BMJ
Background Despite considerable interest, the population-based frequency, clinical characteristics and natural history of cognitive impairment in amyotrophic lateral sclerosis (ALS) are not known. Methodology The authors undertook a prospective population-based study of cognitive function in 160 incident Irish ALS patients and 110 matched controls. Home-based visits were conducted to collect demographic and neuropsychological data. Patients were classified using the recently published consensus criteria and by a domain-based classification of both executive and non-executive cognitive processes. Results 13.8% of patients fulfilled the Neary criteria for frontote...
free text keywords: Surgery, Psychiatry and Mental health, Clinical Neurology, Pathology, medicine.medical_specialty, medicine, Neuropsychology, Pediatrics, Cognition, Executive dysfunction, Psychiatry, Dementia, medicine.disease, Frontotemporal dementia, Motor neurone disease, business.industry, business, Amyotrophic lateral sclerosis, Population, education.field_of_study, education
Funded by
European multidisciplinary ALS network identification to cure motor neuron degeneration
  • Funder: European Commission (EC)
  • Project Code: 259867
  • Funding stream: FP7 | SP1 | HEALTH
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