publication . Article . Other literature type . 2006

The fornix and mammillary bodies in older adults with Alzheimer's disease, mild cognitive impairment, and cognitive complaints: a volumetric MRI study.

Brittany R. Copenhaver; Alexander C. Mamourian; Laura A. Rabin; Laura A. Rabin; Robert B. Santulli; Laura A. Flashman; Heather A. Wishart; Andrew J. Saykin; Tara L. McHugh; Robert M. Roth;
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  • Published: 01 Oct 2006 Journal: Psychiatry Research: Neuroimaging, volume 147, pages 93-103 (issn: 0925-4927, Copyright policy)
  • Publisher: Elsevier BV
Abstract
Abstract The fornix and mammillary bodies are important limbic structures that have not been systematically investigated in the earliest stages of preclinical dementia. The present study examined volumetric changes in the fornix and mammillary bodies and improved previously established tracing guidelines to increase reliability and provide more comprehensive measurements. Volumetric measurements were made in euthymic older adults, including 16 patients with mild Alzheimer's disease (AD), 20 patients with amnestic mild cognitive impairment (MCI), 20 individuals with cognitive complaints (CC) but normal neuropsychological test performance, and 20 demographically m...
Subjects
free text keywords: Radiology Nuclear Medicine and imaging, Psychiatry and Mental health, Neuroscience (miscellaneous), Atrophy, medicine.disease, medicine, Degenerative disease, Audiology, medicine.medical_specialty, Central nervous system disease, Fornix, Mammillary body, Alzheimer's disease, Pathology, Psychology, Cognitive disorder, Neuropsychological test, medicine.diagnostic_test
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